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Myelin is found in the membrane sheath that is formed by Schwann cells in the nervous system. It is formed of both lipid and protein components (Norton & Poduslo, J. Neurochem., 21, 749-757, 1973). The chief lipids are cholesterol phosphatides and cerebrosides; and a high degree of unsaturation is a characteristic feature of myelin lipids. Many of the proteins found in myelin are integral components of the membrane, the major ones being glycoproteins with molecular weights around 70,000 (Salzer et al, J. Cell. Biol., 104, 957-965).

The protein is assayed by electrophoresis on agarose gels.

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